Skin allergy Research Paper Example | Topics and Well Written Essays - 750 words

Skin allergy - Research Paper eventUrticaria or hives is an itchy rash, due to hypersensitive reaction by the skin (Linscott, Emedicine). The embodiment may be acute or chronic and there are some(prenominal) variants to this condition. Itching peck occur without any rash and may be due to some disease related to that incite of the skin. Even some medications can cause itching.As far as atopic dermatitis is concerned, the cause is actually unknown. However, several researchers have attributed genetic and environmental mechanisms to the development of atopic dermatitis. Factors which contribute to the development of atopic dermatitis are infection, poor hygiene, extremes of climate, food antigens and aeroallergens (Kraffchik, Emedicine). some(prenominal) chemicals sensitize the skin and cause allergic contact dermatitis. Some of the important chemicals are poison ivy, Nickel, synthetic rubber gloves, p-phenylenediamine, dyes, formaldehyde, wash and wear chemicals and preservativ es (Hogan, Emedicine). In urticaria, the cause is unknown most of the times. However, ingections, foods, stress, drugs, exposure to certain temperatures and climates and exposure to latex paint can trigger the development of the condition (Linscott Emedicine).In atopic dermatitis, the pathophysiology is poorly understood. However, it has been thought that sensitization of IgE and epithelial barrier disturbance secondary to some kind of immune dysfunction is the cause for the allergic rashes. other important defect attributed to this condition is defective epithelial cells contributing to defective barrier mechanism (Kraffchik, Emedicine). The of import immune disturbance is imbalance in the T-lymphocytes with TH2 cells dominating the system and causing release of cytokines like granulocyte macrophage stimulate factor and interleukins 4,5, 12 and 13. All these amount to an increase in IgE levels and fall in interferon da Gamma levels. In those with chronic